An MSP HIPAA compliance checklist needs to go beyond merely ticking off technical controls to navigating the operational realities of a dynamic hospital environment. There's an inherent tension between making systems both highly secure and highly available when clinicians need them.
Maintaining uptime while enforcing safeguards
In a healthcare context, maintaining operations is non-negotiable. In addition to endangering lives, downtime can cost hospitals $1 million or more per day. Defense-in-depth is all about resiliency and layers of protection. If a ransomware attack gets by the primary layers of defense, a hospital must be able to recover quickly. An MSP must design a system with redundant data paths and automated cloud backups. HIPAA requires disaster recovery (DR) plans to be tested regularly.
Managing vendor and remote access
The healthcare supply chain is a complex web of providers, telemedicine platforms, insurers, billing firms, and other third parties. Increasingly, attackers are targeting these vendors to gain access to potentially thousands of downstream clients (as seen in the Change Healthcare attack). In 2024, 88% of major healthcare breaches involved third parties.
An MSP should maintain a comprehensive list of every outside supplier with network access, categorized by risk level based on the type of data they handle. They should also implement zero-trust network access (ZTNA) to ensure that vendors can access only necessary systems and data.
Documenting processes for audits
Under the proposed HIPAA updates, the Office for Civil Rights (OCR) would place greater emphasis on proactive, periodic audits—including audits of business associates. Healthcare organizations would also be required to complete a formal gap analysis every 12 months.
For MSPs supporting healthcare clients, this raises the stakes for documentation. During an audit or after a breach, it is not enough to say safeguards were in place. Organizations must be able to prove it. That means maintaining the compliance artifacts that show which controls were active, when they were active, and how they were monitored.
MSPs also play an important role in supporting annual risk assessments. This often includes running technical vulnerability scans, identifying gaps such as unpatched servers, and documenting "predisposing conditions" that could increase the likelihood of a security incident.
If the proposed HIPAA rule changes are finalized, the burden will become even higher. Safeguards that were previously considered "addressable" would become "required." In practice, that means organizations would have far less flexibility to skip a control or rely on an alternative workaround. Nearly every safeguard would need to be implemented, documented, and ready to defend during an audit.
Data protections
Under the proposed HIPAA rule changes, ePHI must be protected whether it's "at rest" (stored on a disk) or "in transit" (moving across the network). For data at rest, encryption (ideally AES-256) ensures that if a laptop containing PHI is stolen or a hospital database compromised, the bad actor is blocked from accessing the data.
Under "Safe Harbor" rules, the incident may be exempted from breach notification requirements. For the ease of care, when a doctor logs in (e.g., using a badge tap), the electronic health record (EHR) system temporarily "unlocks" the patient's data in the computer's RAM and locks it again after logging off.
All data moving over the internet, from patient emails to data sent to a cloud lab, must be encrypted using secure protocols like TLS 1.2 or 1.3 (preferred).